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Arrays of numerous spots containing specific oligonucleotides, DNA, proteins, peptides or other small molecules chemically attached to a substrate and organized in a grid on a supporting material; probe-based technique used in biochemistry and genetics.
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Ubiquitin-K29R is recombinant ubiquitin with a single substitution of arginine for lysine at position 29. Notable, ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Ubiquitin moieties can subsequently be conjugated to this initial ubiquitin. This utilizes any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This mutation will ensure chains will not form at mutated lysine to arginine peptide and if mutation causes any functional differences. Need assistance with our products? Contact us here at customerservice@lifesensors.com.
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This gene encodes ubiquitin one of the most conserved proteins known Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome It is also involved in the maintenance of chromatin structure the regulation of gene expression and the stress response Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence Consequently the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat An aberrant form of this protein has been detected in patients with Alzheimer s disease and Down syndrome Pseudogenes of this gene are located on chromosomes 1 2 13 and 17 Alternative splicing results in multiple transcript variants
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Differs structurally from JWH 081 by having the methoxy group attached to the naphthyl rings at the 3 position, instead of the 4 position; intended for forensic and research purposes
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StabilCoat™ Plus Stabilizer protects the activity of proteins while simultaneously blocking nonspecific binding sites on microspheres. In microarray applications, the conformation and activity of proteins are effectively preserved in a dried state when stored with StabilCoat™ Plus stabilizer. The product ultimately increases signal and reduces background to improve the sensitivity of assays.
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Differs structurally from JWH 081 by having the methoxy group attached to the naphthyl rings at the 6 position, instead of the 4 position; intended for forensic and research purposes
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Differs structurally from JWH 081 by having the methoxy group attached to the naphthyl rings at the 6 position, instead of the 4 position; intended for forensic and research purposes
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PIP Arrays are 4 x 5 cm hydrophobic membranes that have been spotted with a concentration gradient of all eight phosphoinositides. They are used to determine the relative degree of binding of your protein of interest towards one or more of these lipids in a simple protein lipid overlay assay. Bound protein is then detected by an antibody against the protein or affinity tag. This item is non returnable
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